Executive Summary
Lipoprotein(a) [Lp(a)] is a genetically determined risk factor affecting 20% of the population, conferring up to 3-fold increased risk for cardiovascular events. This white paper proposes implementing one-time pediatric screening for Lp(a) as a cost-effective strategy for early identification of at-risk individuals and implementation of preventive interventions.
Given that Lp(a) levels are primarily genetically determined and remain relatively stable throughout life, a single measurement during childhood can provide lifelong risk stratification information, enabling early lifestyle modifications and targeted therapeutic interventions.